Using The 6 Minute Walk Test

Advancements in the treatment of cardiovascular disease (CVD) has led to improved prognosis in recent years; however, healthcare utilization and costs has also increased (1-3). The World Health Organization reported that annual medical spending on CVD is expected to reach $818 billion by 2030. 

Exacerbation is common in this population and further reduces physical function, leading to increased hospital readmission risk and costs (1-4). Physical therapists play a key role in improving physical function which significantly reduces the risk of readmission and improves quality of life.

It is important that PTs are able to measure functional capacity and identify high risk patients with CVD, heart failure, and other cardiac conditions as well as those with chronic respiratory disease. While a maximal test such as the cardiopulmonary exercise test holds the place as the gold standard in this type of evaluation, performing this test is not always feasible. An alternative that is easy to administer with minimal equipment is the 6-minute walk test (6MWT). 

The value of the 6MWT test goes beyond measures for cardiac and respiratory concerns. Today, this test is administered to monitor aspects of health and functional status as well as determine effectiveness of interventions in a wide array of populations.

Which Patients is the 6 Minute Walk Test Used For?

To be clinically useful for a given patient population, an outcome measure must first be reliable. That is, the test must produce consistent results under different conditions (i.e., over time, by different different clinicians).

The 6MWT has acceptable (ICC>0.8) test-retest reliability for:

  • Alzheimer’s Disease/Dementia (5,6)
  • Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) (7)
  • Chronic Obstructive Pulmonary Disease (COPD) (8)
  • Community-Dwelling Older Adults (9)
  • Coronary Artery Disease (10)
  • Duchenne Muscular Dystrophy (11)
  • Heart Failure (12)
  • Huntington Disease (13)
  • Kidney Disease on Hemodialysis (14)
  • Multiple Sclerosis (15)
  • Myasthenia Gravis 16)
  • Parkinson’s Disease (17)
  • Stroke (18)
  • Total Hip/Knee Replacement (19)
  • Traumatic Brain Injury (20)

What Does the 6 Minute Walk Test Measure?

The 6MWT can be used for a variety of purposes, from response to therapy to indications of disease severity and predictions of mortality.

As a measure of functional status, the 6MWT is useful for:

  • Acute respiratory distress syndrome (ARDS)
  • Cardiac surgery
  • COPD
  • Coronary artery disease
  • Heart failure
  • Hip fracture
  • Older adults (age 60-101)
  • Osteoarthritis
  • Peripheral arterial disease
  • Pulmonary arterial hypertension

 

6MWT can be used as a predictive measure of hospitalization, poor outcomes, mortality and/or morbidity in:

  • Cancer
  • Cardiac surgery
  • COPD
  • Heart failure 
  • Peripheral arterial disease 
  • Pulmonary hypertension
  • Restrictive lung disease

 

The test can help indicate progress and performance in response to certain therapies, as well:

  • Acute respiratory distress syndrome (ARDS)
  • Cardiac surgery
  • CIDP
  • COPD
  • Coronary artery disease
  • Heart failure
  • Muscular Dystrophy



How to Administer the 6 Minute Walk Test

Administering the 6MWT requires attention but is relatively straightforward and requires minimal equipment. A physical or occupational therapist can perform the test almost anywhere, from a corridor to a patient’s own home, as long as there is enough clear walkway to set up a track. It is not recommended to perform the 6 MWT outdoors if it can be avoided.

Ideally, the path will be 50 to 100 feet but should be at least 3 meters or 9.8 feet. Measurement of the path will be important when determining results, whether by hand or using a 6-minute walk test calculator.

Equipment Needed for the 6-Minute Walk Test

  • Markers for the path’s endpoints: these could be almost anything that won’t get in the way, from small playground cones to chairs.
  • A means of measuring the distance between endpoints of the path: a tape measure or even squares of tile can help measure the distance.
  • Timing device: A stopwatch or watch.
  • A chair for resting, if needed.

Setting up the 6-Minute Walk Test

  1. Measure and mark the walking path.
  2. Set the patient up to begin at one end of the marked path.
  3. Upon the nurse or therapist saying “Go”, the timer should be started and the patient will walk back and forth between the marked endpoints for 6 minutes.
  4. The patient may stop during the test if they need to rest, but the timer should continue to run.
  5. When the time is complete, the patient should stop where they are. Measure the final distance and allow the patient to rest.

If you will be administering the test more than once on the same day the patient should be given a 30-minute break between tests.

Which Actions Should the Clinician Take During the 6-Minute Walk Test?

As the practitioner administering the test, you should plan to do the following:

  1. Keep an eye on the time.
  2. Monitor the patient closely for distress.
  3. Keep a chair at hand in case the patient needs to rest during the test.
  4. Ensure measurements – distance, time, etc. – are recorded and computed accurately.
  5. At the end of each minute, give the patient encouragement without indicating performance, and inform them of the time remaining. For instance, you could say:
    – “You’ve got 5 minutes remaining. You’re doing well.”
    – “Good job. You have 4 minutes remaining.”
    – and so on.
  6. Make sure that the patient stops in place at the end of the 6 minutes.

Interpreting Test Results 

Six-minute walk test norms are variable by population demographics, physical attributes, track size, and presenting conditions. For instance, patients who walked in one direction on a track tended to walk further distances than those asked to walk back and forth (Scivoletto et al, 2011). Re-tests should be performed in a manner consistent with the initial testing.

Normative Data

The following scores are considered “worse than average” for their respective age groups: (Lusardi et al, 2003)

  • 60-69 yrs: < 420 meters 
  • 70-79 yrs: < 439 meters
  • 80-89 yrs: < 292 meters
  • 90-101 yrs: < 265 meters

Cut-Off Scores

Chronic Obstructive Pulmonary Disorder (COPD)

  • <350 meters is associated w/ increased mortality, airflow limitation, dyspnea, depressive symptoms, & overall poor prognosis (Spruit et al, 2010).

Heart Failure

  • Those who walk <522 meters are more likely to develop functional impairment (Costa et al, 2014)
  • <468 meters is associated with ~3x greater risk of hospitalization or death in one year (Wergrzynowska-Teodorcyk, 2013; Ferreira, 2019)

Left Ventricular Assist Device (LVAD)

  • <300 meters is associated with poor exercise tolerance, worse quality of life; higher frequencies of bleeding, infection, right heart failure, & cardiac arrhythmias post-operatively 
  • Each 10 meters less than <300 meters is associated with 21% greater risk of mortality (Hasin et al, 2012)

Lung Cancer

  • <305 meters is predictive of unsuccessful surgical outcome after pulmonary resection surgery (≤90 day survival) (Holden, 1992)

Pulmonary Hypertension

  • <332 meters is associated with significantly lower 2-yr survival rate (Miyamoto et al, 2000)

Stroke

  • Those walking <205 meters are likely limited to household ambulation; require assistance for community mobility (Fulk et al, 2017)

Accurate measurement is key to identifying high risk patients, developing a plan of care, and determining treatment efficacy. While it’s possible to use pencil and paper, there are readily available 6MWT calculators available for mobile devices that can remove the time and energy required to perform calculations, interpret results, and document findings.

Measuring up the value of physical therapy

A Leading Tool In Quality Care & Outcome Measures

References

  1. Butler J, Kalogeropoulos A: Hospital strategies to re- duce heart failure readmissions: where is the evidence? J Am Coll Cardiol 2012;60:615–617. PMID:22818073, DOI:10.1016/j.jacc.2012.03.066
  2. Gheorghiade M, Vaduganathan M, Fonarow GC, Bonow RO: Rehospitalization for heart failure: prob- lems and perspectives. J Am Coll Cardiol 2013;61:391– 403. PMID:23219302, DOI:10.1016/j.jacc.2012.09.038
  3. SperryBW,RuizG,NajjarSS:Hospitalreadmissionin heart failure, a novel analysis of a longstanding prob- lem. Heart Fail Rev 2015;20:251–258. PMID:25287658, DOI:10.1007/s10741-014-9459-2
  4. Gheorghiade M, Follath F, Ponikowski P, Barsuk JH, Blair JE, Cleland JG, Dickstein K, Drazner MH, Fonarow GC, Jaarsma T, Jondeau G, Sendon JL, Me- bazaa A, Metra M, Nieminen M, Pang PS, Seferovic P, Stevenson LW, van Veldhuisen DJ, Zannad F, Anker SD, Rhodes A, McMurray JJ, Filippatos G, European Society of Cardiology European Society of Intensive Care Medicine: Assessing and grading congestionin acute heart failure: a scientific statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology and endorsed by the European Society of Intensive Care Medicine. Eur J Heart Fail 2010;12:423–433.
  5. Chan WLS, Pin TW. Reliability, validity and minimal detectable change of 2-minute walk test, 6-minute walk test and 10-meter walk test in frail older adults with dementia. Exp Gerontol. 2018.
  6. Ries, JD, et al. Test-retest reliability and minimal detectable change scores for the timed up & go test, the six-minute walk test, and gait speed in people with alzheimer disease. Physical Therapy. 2009;89(6):569-579.
  7. Spina E, Topa A, Iodice R, et al. Six-minute walk test is reliable and sensitive in detecting response to therapy in CIDP. J Neurol. 2019.
  8. Hernandes, Wouters, Meijer, et al. Reproducibility of 6 minute walking test in patients with COPD. European Respiratory Journal. 2011;38:261-267
  9. Steffen TM, Hacker TA, et al. Age- and gender-related test performance in community-dwelling elderly people: six-minute walk test, berg balance scale, timed up & go test, and gait speeds. Physical Therapy.  2002;82(2):128-137.
  10. Bellet RN, Adams L, Morris NR. The 6-minute walk test in outpatient cardiac rehabilitation: validity, reliability and responsiveness–a systematic review. Physiotherapy. 2012;98:277–286.
  11. McDonald CM, Henricson EK, Abresch RT, et al. The 6-minute walk test and other clinical endpoints in duchenne muscular dystrophy: reliability, concurrent validity, and minimal clinically important differences from a multicenter study. Muscle & Nerve. 2013;48(3):357-368.
  12. Demers C, McKelvie RS, Negassa A, Yusuf S. Reliability, validity, and responsiveness of the six-minute walk test in patients with heart failure. Am Heart J, 142. 2001;698-703.
  13. Quinn L, Khalil H, Dawes H, et al. Reliability and minimal detectable change of physical performance measures in individuals with pre-manifest and manifest Huntington disease. Phys Ther. 2013;93(7):942–56.
  14. Segura-Orti E, Martinez-Olmos FJ. Test-retest reliability and minimal detectable change scores for sit-to-stand-to-sit tests, the six-minute walk test, the one-leg heel-rise test, and handgrip strength in people undergoing hemodialysis. Phys Ther. 2011;91:1244-1252.
  15. Decavel P, Moulin T, Sagawa Y. Gait tests in multiple sclerosis: Reliability and cut-off values. Gait & Posture. 2019;67:37-42.
  16. Resqueti, Oliveira, Dourado, et al. Reliability of the six-minute walk test in patients with generalized myasthenia gravis. Fisioterapia e Pesquisa. 2009;16(3):223–228.
  17. Steffen T & Seney M. Test-retest reliability and minimal detectable change on balance and ambulation tests, the 36-item short-form health survey, and the unified parkinson disease rating scale in people with parkinsonism. Physical Therapy. 2008;88(6).
  18. Eng JJ, Dawson AS, et al. Submaximal exercise in persons with stroke: test-retest reliability and concurrent validity with maximal oxygen consumption. Arch Phys Med Rehabil. 2004;85(1):113-118.
  19. Kennedy DM, Stratford PW, Wessel J, et al. Assessing stability and change of four performance measures: a longitudinal study evaluating outcome following total hip and knee arthroplasty. BMC Musculoskeletal Disorders. 2005;6:3.
  20. Mossberg KA. Reliability of a timed walk test in persons with acquired brain injury. Am J Phys Med Rehabil. 2003;82(5):385-390.
  21. Balke B. A simple field test for the assessment of physical fitness. Rep Civ Aeromed Res Inst US. 1963(53):1 – 8.
  22. Troosters T, Gosselink R, Decramer M. Six minute walking distance in healthy elderly subjects. Eur Respir J. 1999 Aug;14(2):270-4
  23. Mudge S, Stott NS. Timed walking tests correlate with daily step activity in persons with stroke. Archives of physical medicine and rehabilitation. 2009; 90(2):296-301.
  24. Focht B, Rejeski WJ, Ambrosius W, Katula J, Messier S. Exercise, self-efficacy, and mobility performance in overweight and obese older adults with knee osteoarthritis. Arthritis and rheumatism. 2005;53(5):659-65.
  25. Lord S, Menz H. Physiologic, psychologic, and health predictors of 6-minute walk performance in older people. Archives of physical medicine and rehabilitation. 2002; 83(7):907-11.
  26. Gulmans VAM, vanVeldhoven NHMJ, deMeer K, Helders PJM. The six-minute walking test in children with cystic fibrosis: reliability and validity. Pediatr Pulmonol 1996;22:85–89.
  27. King S, Wessel J, Bhambhani Y, Maikala R, Sholter D, Maksymowych W. Validity and reliability of the 6 minute walk in persons with fibromyalgia. J Rheumatol 1999;26:2233–2237.
  28. Scivoletto, G., Tamburella, F., et al. (2011). “Validity and reliability of the 10-m walk test and the 6-min walk test in spinal cord injury patients.” Spinal Cord 49(6):736-740.
  29. Ferreira JP, Metra M, Anker SD, et al. Clinical correlates and outcome associated with changes in 6-minute walking distance in patients with heart failure: findings from the BIOSTAT-CHF study. European Journal of Heart Failure. 2019.
  30. Ruhl AP, Huang M, Colantuoni E, et al. Healthcare Resource Use and Costs in Long-Term Survivors of Acute Respiratory Distress Syndrome/ A 5-Year Longitudinal Cohort Study. Crit Care Med. 2017;45(2)/196–204. doi/10.1097/CCM.0000000000002088.
  31. Castel MA, Méndez F, Tamborero D, et al. Six-minute walking test predicts long-term cardiac death in patients who received cardiac resynchronization therapy/ EP Europace. 2009;11(3):338-342.
  32. Holden, DA, Rice, TW, Stelman, K et al. Exercise testing, 6-min walk, and stair climb in the evaluation of patients at high risk for pulmonary resection. Chest. 1992; 102: 1774–1779
  33. Lusardi M. Functional Performance in Community Living Older Adults.  Journal of Geriatric Physical Therapy. 2003. 26(3):14-22.

 

Comments are closed.